RT Journal Article
SR Electronic
T1 Incidental Endometrial Adenocarcinoma in Early Pregnancy: A Case Report and Review of the Literature
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP 1580
OP 1584
DO 10.1111/IGC.0b013e3181a841a7
VO 19
IS 9
A1 Hannuna Karen Yael
A1 Putignani Lorenza
A1 Silvestri Evelina
A1 Pisa Roberto
A1 Angioli Roberto
A1 Signore Fabrizio
YR 2009
UL http://ijgc.bmj.com/content/19/9/1580.abstract
AB Endometrial cancer is the most common neoplasia of the female reproductive system, with the highest incidence among uterine malignancies, and is rarely associated with pregnancy. Thirty-five cases of pregnancy-associated endometrial cancer have been reported in literature, of which ours represents the 20th case diagnosed during the first trimester. A 39-year-old woman, gravida 4, para 2, was diagnosed with a focal, well- to moderately differentiated endometrial adenocarcinoma (International Federation of Gynecology and Obstetrics stage IA and grades G1 and G2) after dilatation and curettage (D&C) for a spontaneous abortion. The patient underwent progestational therapy and follow-up hysteroscopies and D&C to preserve fertility; she is alive and well 18 months after diagnosis. Recurrence of endometrial cancer coexisting with early pregnancy has not been reported in the literature. Conservative therapy for early endometrial cancer, diagnosed at the time of pregnancy, may be an option. Routine histologic examination after D&C performed for spontaneous abortion seems advisable.