TY - JOUR T1 - Cervical Carcinoma: Postoperative Radiotherapy: Fifteen-Year Experience in a Norwegian Health Region JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - 1595 LP - 1599 DO - 10.1111/IGC.0b013e3181bed288 VL - 19 IS - 9 AU - Elke Lorenz AU - Trond Strickert AU - Bjørn Hagen Y1 - 2009/11/01 UR - http://ijgc.bmj.com/content/19/9/1595.abstract N2 - Introduction: To study the results in cervical carcinoma after a combined treatment with surgery and radiotherapy with regard to survival and side effects.Methods: A retrospective analysis of 71 patients who underwent radical hysterectomy and postoperative radiotherapy between January 1, 1987, and December 31, 2001, was performed.Results: Median follow-up periods were 162 months for surviving patients and 62 months for deceased patients. The 5-year overall survival and disease-specific survival for all stages were 80.3% and 82.7%, respectively. The 5-year actuarial incidence of late reactions for grade 1 + 2 was as follows: for upper gastrointestinal tract, 36%; for rectum, 37%; for urinary tract, 19%; for vagina, 26%; and for lymph edema, 19%. The 5-year actuarial incidence of late reactions for grade 3 + 4 was as follows: for upper gastrointestinal tract, 12%; and for rectum, 3%.Conclusions: Careful pretreatment workup and well-defined criteria for postoperative radiotherapy are essential, and new treatment options such as intensity-modulated radiation therapy should be considered. ER -