TY - JOUR T1 - Effects of Previous Surgery on the Detection of Sentinel Nodes in Women With Vulvar Cancer JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - 1679 LP - 1683 DO - 10.1097/IGC.0b013e31822dbe3c VL - 21 IS - 9 AU - Tessa A. Ennik AU - David G. Allen AU - Ruud L.M. Bekkers AU - Simon E. Hyde AU - Peter T. Grant Y1 - 2011/11/01 UR - http://ijgc.bmj.com/content/21/9/1679.abstract N2 - Background There is a growing interest to apply the sentinel node (SN) procedure in the treatment of vulvar cancer. Previous vulvar surgery might disrupt lymphatic patterns and thereby decrease SN detection rates, lengthen scintigraphic appearance time (SAT), and increase SN false-negative rate. The aims of this study were to evaluate the SN detection rates at the Mercy Hospital for Women in Melbourne and to investigate whether previous vulvar surgery affects SN detection rates, SAT, and SN false-negative rate.Methods Data on all patients with vulvar cancer who underwent an SN procedure (blue dye, technetium, or combined technique) from November 2000 to July 2010 were retrospectively collected.Results Sixty-five SN procedures were performed. Overall detection rate was 94% per person and 80% per groin. Detection rates in the group of patients who underwent previous excision of the primary tumor were not lower compared with the group without previous surgery or with just an incisional biopsy. There was no statistical significant difference in SAT between the previous excision group and the other patients. None of the patients with a false-negative SN had undergone previous excision.Conclusions Results indicate that previous excision of a primary vulvar malignancy does not decrease SN detection rates or increase SN false-negative rate. Therefore, the SN procedure appears to be a reliable technique in patients who have previously undergone vulvar surgery. Previous excision did not significantly lengthen SAT, but the sample size in this subgroup analysis was small. ER -