PT  - JOURNAL ARTICLE
AU  - J. Balega
AU  - T. M. Ulbright
AU  - K. Y. Look
TI  - Coexistence of metastatic neuroendocrine carcinoma of the uterine cervix with human immunodeficiency virus infection
AID  - 10.1136/ijgc-00009577-200107000-00017
DP  - 2001 Jun 01
TA  - International Journal of Gynecologic Cancer
PG  - 334--337
VI  - 11
IP  - 4
4099  - http://ijgc.bmj.com/content/11/4/334.short
4100  - http://ijgc.bmj.com/content/11/4/334.full
SO  - Int J Gynecol Cancer2001 Jun 01; 11
AB  - Abstract. Balega J, Ulbright TM, Look KY. Coexistence of metastatic neuroendorcine carcinoma of the uterine cervix with human immunodeficiency virus infection.Women now constitute 28% of new cases of human immunodeficiency virus (HIV) infection. Cervical cancer in HIV-infected women has a high recurrence and death rate, as well as decreased intervals to recurrence and death. Neuroendocrine carcinomas of the cervix are characterized by a high frequency of early nodal and distant metastases.We present the first report of a neuroendocrine carcinoma of the cervix in an HIV-positive patient. A 28 year old with a 9-year history of HIV succumbed to metastatic neuroendocrine carcinoma of the cervix 5 months after diagnosis.Given the aggressive nature of the cell type, an extended metastatic workup should be considered prior to surgery. The immune suppression present in HIV-positive patients with neuroendocrine cervical carcinoma may make such a workup particularly crucial, such that surgery is offered only to those who can be expected to benefit.