RT Journal Article
SR Electronic
T1 Extraperitoneal metastases after intraperitoneal chemotherapy of ovarian cancer patients with a negative second-look laparotomy
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP 359
OP 362
DO 10.1046/j.1525-1438.1993.03060359.x
VO 3
IS 6
A1 J. Menczer
A1 G. Ben-Baruch
A1 S. Rizel
A1 H. Brenner
YR 1993
UL http://ijgc.bmj.com/content/3/6/359.abstract
AB The site of the first detectable recurrence was recorded in 17 consecutive stage II–IV ovarian carcinoma patients who, after a negative second-look laparotomy, received intraperitoneal chemotherapy with cisplatin and thiosulfate kidney protection. Although the progression-free interval and survival were favorable, 11 patients eventually had a recurrence and in six (54.5%) of these it was extraperitoneal. Brain metastases were detected in three patients. The appearance of extraperitoneal metastases is not always ominous.