RT Journal Article
SR Electronic
T1 Accuracy of cervical smears in predicting the grades of cervical intraepithelial neoplasia
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP 89
OP 93
DO 10.1046/j.1525-1438.1993.03020089.x
VO 3
IS 2
A1 A. I. Al-Nafussi
A1 M. K. Colquhoun
A1 A. R.W. Williams
YR 1993
UL http://ijgc.bmj.com/content/3/2/89.abstract
AB This is a retrospective study carried out to assess the correlation between the cytology and histology of cervical intraepithelial neoplasia in 1325 women. A poor correlation between the cytologic and histologic diagnosis of the various grades of CIN was shown. Forty-one percent of smears with repeated borderline change and 50% of those predicting CIN1 showed a higher grade of CIN on histology. The overall apparent false negative rate of cervical smears for high grade CIN (CIN2 and CIN3) was 19% and for CIN3 alone was only 3%. It is therefore concluded that there is a consistent tendency for cervical cytology to underestimate the severity of histologic lesions and it is therefore important that the clinicians ensure adequate follow-up of patients whose smears show a lesser degree of abnormality.