RT Journal Article SR Electronic T1 Effect of a Complementary/Integrative Medicine Treatment Program on Taxane-Induced Peripheral Neuropathy: A Brief Report JF International Journal of Gynecologic Cancer JO Int J Gynecol Cancer FD BMJ Publishing Group Ltd SP 1045 OP 1049 DO 10.1097/IGC.0000000000001246 VO 28 IS 5 A1 Eran Ben-Arye A1 Yaron River A1 Yael Keshet A1 Ofer Lavie A1 Pesi Israeli A1 Noah Samuels YR 2018 UL http://ijgc.bmj.com/content/28/5/1045.abstract AB Objective Peripheral neuropathy is a common complication of cancer treatment impairing quality of life and function. This study explored the impact of a complementary and integrative medicine (CIM) program on taxane-induced peripheral neuropathy (TIPN).Materials and Methods Taxane-treated female patients with breast and gynecological cancer reporting TIPN-related symptoms were referred to an integrative physician, followed by patient-tailored CIM treatments (acupuncture with/without other modalities). Assessment of study outcomes at 6 to 12 weeks was conducted using the Measure Yourself Concerns and Wellbeing, which documented free-text narratives about patients’ experience during the CIM treatment process. Content was analyzed using ATLAS.Ti software.Results Of the 125 patients treated with taxanes, 69 had been referred for CIM treatment of TIPN-associated symptoms. Multidisciplinary narrative analysis identified 2 groups of CIM-treated patients: those with an apparently moderate improvement in symptoms (n = 35) and those with either only an apparent mild or no improvement at all. For 10 patients, assessment of their response to treatment was unclear. The 2 identified groups had similar demographic, cancer-related, and quality of life–related parameters at baseline. Content analysis of patients with an apparent moderate improvement suggested a short-term (24–48 hours) effect with acupuncture treatment, either alone or combined with manual, mind-body, and anthroposophic music therapies. Symptoms showing improvement included paresthesia and numbness.Conclusions Acupuncture and other CIM therapies may result in a short-term and transitory reduction in TIPN-related symptoms.