RT Journal Article SR Electronic T1 Addressing Challenges in Future Surveillance After Surgery for Early-Stage Cervical Cancer JF International Journal of Gynecologic Cancer JO Int J Gynecol Cancer FD BMJ Publishing Group Ltd SP 309 OP 314 DO 10.1097/IGC.0000000000000346 VO 25 IS 2 A1 Katrine Fuglsang A1 Lone Kjeld Petersen A1 Jan Blaakaer YR 2015 UL http://ijgc.bmj.com/content/25/2/309.abstract AB Objective This study examines surveillance after early-stage cervical cancer surgery. Since the 1980s, the value of surveillance has been discussed continuously. The main question explored is whether surveillance serves the purpose of ensuring early diagnosis of recurrence.Materials and Methods A retrospective cohort study included 389 women with cervical cancer who underwent surgery as the primary treatment modality at the Department of Obstetrics and Gynecology, Aarhus University Hospital, Denmark, from 1996 to 2011. We used data from patient files and the Danish National Pathology Data Bank. The cumulative risk was estimated by the Kaplan-Meier method and tested by the log-rank test.Results Forty-three women (11%) had recurrence. Only 27% of the recurrent cases were diagnosed at a scheduled surveillance appointment, but they were often asymptomatic and seemed to have a better outcome after treatment compared with the recurrent cases diagnosed at self-referral.The 5-year survival was overall 91.3%, recurrence-free survival was 96%, and cancer-specific survival was 54%. The median recurrence-free interval was 23 months (range, 4–144) for the symptomatic patients and 14 months (range, 4–48) for the asymptomatic patients. The median survival after recurrence was 12 months (range, 2–132) for the symptomatic patients and 156 months (range, 40–180) for the asymptomatic patients.Conclusions At the moment, neither the value of surveillance nor the significance of self-referral related to survival after recurrence is known. In this study, those who are diagnosed with recurrence before symptom onset seem to fare better in terms of 5-year survival than those who are diagnosed after self-referral because of symptoms.