RT Journal Article SR Electronic T1 Nerve-Sparing Versus Conventional Laparoscopic Radical Hysterectomy: A Minimum 12 Months’ Follow-up Study JF International Journal of Gynecologic Cancer JO Int J Gynecol Cancer FD BMJ Publishing Group Ltd SP 787 OP 793 DO 10.1097/IGC.0000000000000110 VO 24 IS 4 A1 Giorgio Bogani A1 Antonella Cromi A1 Stefano Uccella A1 Maurizio Serati A1 Jvan Casarin A1 Ciro Pinelli A1 Federica Nardelli A1 Fabio Ghezzi YR 2014 UL http://ijgc.bmj.com/content/24/4/787.abstract AB Objective The objective of this study was to determinate whether the introduction of nerve-sparing (NS) procedure influences surgical and survival outcomes of cervical cancer patients undergoing laparoscopic radical hysterectomy (LRH).Methods Data of consecutive patients undergoing minimally invasive radical with or without NS surgery for cervical cancer were enrolled in the study.Results Sixty-three patients (66%) who had LRH were compared with 33 women (34%) undergoing NS-LRH. Among the NS group, 19 patients (57.6%) had surgery via minilaparoscopy (using 3-mm instruments). Baseline characteristics were similar between groups. Patients undergoing NS-LRH had shorter operative time (210 vs 257 minutes; P = 0.005) and higher number of pelvic lymph nodes yielded (29 [26–38] vs 22 [8–49]; P < 0.001) than patient in the control group. No differences in blood loss, complications, and parametrial width were observed. Patients were catheterized with an indwelling Foley catheter for a median of 3.5 days (2–7 days) and 5.5 days (4–7 days) in NS and non-NS groups, respectively (P = 0.01). Voiding dysfunctions occurred in 1 patient (3%) and 12 patients (19%) who underwent NS-LRH and standard LRH, respectively (P = 0.03). No differences in 3-year disease-free survival (P = 0.72) and overall survival (P = 0.71) were recorded.Conclusions The beneficial effects (in terms of operative time and number of nodes harvested) of NS-LRH are likely determined by the expertise of the surgeon because NS approach was introduced after having acquired adequate background in conventional LRH. Our data show that in experienced hands NS-LRH is safe and feasible. Moreover, NS technique reduces catheterization time and the rate of postoperative urinary dysfunction.