TY - JOUR T1 - Causes and Palliation of Transfusion-Associated Vaginal Bleeding in Patients With Metastatic Cancer JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - 172 LP - 175 DO - 10.1097/IGC.0000000000000017 VL - 24 IS - 1 AU - Amie E. Jackson AU - Elisabeth K. Stephens AU - Aminah Jatoi Y1 - 2014/01/01 UR - http://ijgc.bmj.com/content/24/1/172.abstract N2 - Purpose The current study was undertaken (1) to capture a clinically relevant, systematically collected series of patients with metastatic cancer and transfusion-associated vaginal bleeding and (2) to provide insight into how best to palliate this bleeding.Methods/Results As part of a single-institution review, 46 patients with metastatic cancer and transfusion-associated vaginal bleeding were identified. In a minority, 14 (30%), the cancer itself was directly responsible for the bleeding, and under these circumstances, gynecological cancer was the most frequent cause. In 13 patients (28%), more than 1 palliative intervention was attempted. Of all the interventions, a hysterectomy was performed most frequently and was successful in 11 patients. The use of ablation or embolization procedures was rarely tried but successful in 4 patients. However, 2 patients died of vaginal bleeding, despite multiple palliative procedures to control bleeding, including tumor embolization in one.Conclusions Transfusion-associated vaginal bleeding in patients with metastatic cancer can arise from nonmalignant causes and often assumes an uneventful course but can, at times, be serious and difficult to control. ER -