TY - JOUR T1 - Treatment Patterns, Health Care Utilization, and Costs of Ovarian Cancer in Central and Eastern Europe Using a Delphi Panel Based on a Retrospective Chart Review JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - 823 LP - 832 DO - 10.1097/IGC.0b013e318291e8ca VL - 23 IS - 5 AU - Kun Kim AU - Emma Hernlund AU - Zoltán Hernadi AU - János Révész AU - Imre Pete AU - András Szánthó AU - Lubomir Bodnar AU - Rodoslaw Madry AU - Agnieszka Timorek–Lemieszczuk AU - Tatjana Bozanovic AU - Suzana Vasovic AU - Zorica Tomasevic AU - Milica Zivaljevic AU - Vladimir Pazin AU - Tomáš Minárik AU - Hana Garanová AU - Lýdia Heľpianska AU - Nahila Justo Y1 - 2013/06/01 UR - http://ijgc.bmj.com/content/23/5/823.abstract N2 - Objective Despite the considerable disease burden of ovarian cancer, there were no cost studies in Central and Eastern Europe. This study aimed to describe treatment patterns, health care utilization, and costs associated with treating ovarian cancer in Hungary, Poland, Serbia, and Slovakia.Method Overall clinical practice for management of epithelial ovarian cancer was investigated through a 3-round Delphi panel. Experts completed a survey based on the chart review (n = 1542). The survey was developed based on clinical guidelines and the International Federation of Gynecology and Obstetrics Annual Report. Means, ranges, and outlier values were discussed with the experts during a telephone interview. Finally, consensus estimates were obtained in face-to-face workshops. Based on these results, overall cost of ovarian cancer was estimated using a Markov model.Results The patients included in the chart review were followed up from presurgical diagnosis and in each phase of treatment, that is, surgical staging and primary surgery, chemotherapy and chemotherapy monitoring, follow-up, and palliative care. The 5-year overall cost per patient was €14,100 to €16,300 in Hungary, €14,600 to €15,800 in Poland, €7600 to €8100 in Serbia, and €12,400 to €14,500 in Slovakia. The main components were chemotherapy-associated costs (68%–74% of the total cost), followed by cost of primary treatment with surgery (15%–21%) and palliative care (3%–10%).Conclusions Patients with ovarian cancer consume considerable health care resources and incur substantial costs in Central and Eastern Europe. These findings may prove useful for clinicians and decision makers in understanding the economic implications of managing ovarian cancer in Central and Eastern Europe and the need for innovative therapies. ER -