RT Journal Article SR Electronic T1 EP378/#519  Cervical cancer prevention program in Nepal: a comprehensive ‘train the trainer’ approach JF International Journal of Gynecologic Cancer JO Int J Gynecol Cancer FD BMJ Publishing Group Ltd SP A229 OP A229 DO 10.1136/ijgc-2023-IGCS.427 VO 33 IS Suppl 4 A1 Pariyar, Jitendra A1 Batman, Samantha A1 Piya, Madan A1 Chapagain, Sandhya A1 Lama, Poonam A1 Maharjan, Pabitra A1 Neupane, Maya A1 Phoolcharoen, Natacha A1 Baker, Ellen A1 Varon, Melissa A1 Salcedo, Mila P A1 Milan, Jessica A1 Pariyar, Shashwat A1 Schmeler, Kathleen M YR 2023 UL http://ijgc.bmj.com/content/33/Suppl_4/A229.2.abstract AB Introduction Cervical cancer is a leading cancer in Nepal. Lack of access to screening and trained health professionals to manage preinvasive and invasive cervical disease contributes to high cancer incidence and mortality.Methods Cancer Care Nepal (CCN) and MD Anderson Cancer Center (MD Anderson) partnered to implement a ‘train the trainer’ (TOT) program to teach cervical cancer screening and management. TOT courses were held for specialists from five institutions throughout Nepal to learn how to deliver these trainings. Each participating institution then held local courses for nurses and doctors. The training was complemented with monthly Project ECHO® (Extension for Community Healthcare Outcomes) telementoring videoconferences.Results Two TOT and five local training courses were held for providers from 20 centers from November 2021 to October 2022. During COVID-19 pandemic travel restrictions, the MD Anderson faculty joined the courses and provided didactics virtually. In-person, hands-on training using simulation models to teach VIA, colposcopy, ablation and LEEP were led by the Nepalese faculty. The 173 participants included 28 gynecologists, 4 gynecologic oncologists, 1 medical oncologist, 22 general practitioners, and 118 nurses. 126 (73%) completed the pre- and post-course surveys with 86% of respondents expressing their desire to make changes in their practice as a result of the courses. In 2022, CCN became a Project ECHO hub and has held 12 sessions with approximately 20 participants from 11 centers per session.Conclusion/Implications Our TOT and local training courses have increased the reach of training, with the goal of decreasing the burden of cervical cancer in Nepal.