TY - JOUR T1 - Squamous cell vulvar carcinoma associated with Fanconi's anemia: a case report JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - 220 LP - 222 DO - 10.1136/ijgc-00009577-200203000-00015 VL - 12 IS - 2 AU - J. P Carvalho AU - M. L. Nogueira Dias AU - F. M Carvalho AU - M Del Pilar Estevez Diz AU - J. W Petito Y1 - 2002/03/01 UR - http://ijgc.bmj.com/content/12/2/220.abstract N2 - Fanconi's anemia (FA) is a rare autosomal recessive syndrome associated with a strong predisposition to cancer, particularly squamous cell carcinoma (SCC) of various organs. A few cases of lower genital tract neoplasia have been described. We present a 14-year-old black girl with an advanced squamous cell vulvar carcinoma treated with cisplatin chemotherapy plus radiation therapy. The patient died because of fungal sepsis. Polymerase chain reaction (PCR) was positive to human papillomavirus (HPV)-16. Vulvar carcinoma is a very rare condition in teenagers, but the association of Fanconi's anemia and SCC of many sites is common. Vulvar carcinoma when associated with Fanconi's anemia is a great treatment challenge. ER -