PT  - JOURNAL ARTICLE
AU  - J. P Carvalho
AU  - M. L. Nogueira Dias
AU  - F. M Carvalho
AU  - M Del Pilar Estevez Diz
AU  - J. W Petito
TI  - Squamous cell vulvar carcinoma associated with Fanconi's anemia: a case report
AID  - 10.1136/ijgc-00009577-200203000-00015
DP  - 2002 Mar 01
TA  - International Journal of Gynecologic Cancer
PG  - 220--222
VI  - 12
IP  - 2
4099  - http://ijgc.bmj.com/content/12/2/220.short
4100  - http://ijgc.bmj.com/content/12/2/220.full
SO  - Int J Gynecol Cancer2002 Mar 01; 12
AB  - Fanconi's anemia (FA) is a rare autosomal recessive syndrome associated with a strong predisposition to cancer, particularly squamous cell carcinoma (SCC) of various organs. A few cases of lower genital tract neoplasia have been described. We present a 14-year-old black girl with an advanced squamous cell vulvar carcinoma treated with cisplatin chemotherapy plus radiation therapy. The patient died because of fungal sepsis. Polymerase chain reaction (PCR) was positive to human papillomavirus (HPV)-16. Vulvar carcinoma is a very rare condition in teenagers, but the association of Fanconi's anemia and SCC of many sites is common. Vulvar carcinoma when associated with Fanconi's anemia is a great treatment challenge.