PT - JOURNAL ARTICLE AU - Carvalho, J. P AU - Dias, M. L. Nogueira AU - Carvalho, F. M AU - Del Pilar Estevez Diz, M AU - Petito, J. W TI - Squamous cell vulvar carcinoma associated with Fanconi's anemia: a case report AID - 10.1136/ijgc-00009577-200203000-00015 DP - 2002 Mar 01 TA - International Journal of Gynecologic Cancer PG - 220--222 VI - 12 IP - 2 4099 - http://ijgc.bmj.com/content/12/2/220.short 4100 - http://ijgc.bmj.com/content/12/2/220.full SO - Int J Gynecol Cancer2002 Mar 01; 12 AB - Fanconi's anemia (FA) is a rare autosomal recessive syndrome associated with a strong predisposition to cancer, particularly squamous cell carcinoma (SCC) of various organs. A few cases of lower genital tract neoplasia have been described. We present a 14-year-old black girl with an advanced squamous cell vulvar carcinoma treated with cisplatin chemotherapy plus radiation therapy. The patient died because of fungal sepsis. Polymerase chain reaction (PCR) was positive to human papillomavirus (HPV)-16. Vulvar carcinoma is a very rare condition in teenagers, but the association of Fanconi's anemia and SCC of many sites is common. Vulvar carcinoma when associated with Fanconi's anemia is a great treatment challenge.