PT - JOURNAL ARTICLE AU - Fadi Alfhaily AU - Ayman A. A. Ewies TI - The First-Line Investigation of Postmenopausal Bleeding: Transvaginal Ultrasound Scanning and Endometrial Biopsy May Be Enough AID - 10.1111/IGC.0b013e3181a83387 DP - 2009 Jul 01 TA - International Journal of Gynecologic Cancer PG - 892-895--892-895 VI - 19 IP - 5 4099 - http://ijgc.bmj.com/content/19/5/892-895.short 4100 - http://ijgc.bmj.com/content/19/5/892-895.full SO - Int J Gynecol Cancer2009 Jul 01; 19 AB - Postmenopausal bleeding is a common problem in clinical practice with significant implications; however, the diagnostic strategies often vary among different centers. In the recent years, there was a trend to adopt less invasive procedures without compromising efficacy and safety. There is continuous debate about the different available modalities for investigation, and a large number of studies were conducted to define their roles. Some authors recommended that hysteroscopy should be the standard investigation procedure for women with postmenopausal bleeding. Nonetheless, there is a strong evidence to suggest that transvaginal ultrasound scanning, with or without endometrial biopsy, is a safe and more cost-effective initial tool in investigating these women. This commentary highlights this important issue and discusses the role of these different modalities.