RT Journal Article
SR Electronic
T1 SUCCOR quality: validation of ESGO quality indicators for surgical treatment of cervical cancer
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP 1236
OP 1243
DO 10.1136/ijgc-2022-003790
VO 32
IS 10
A1 Boria, Felix
A1 Chiva, Luis
A1 Chacon, Enrique
A1 Zanagnolo, Vanna
A1 Fagotti, Anna
A1 Kucukmetin, Ali
A1 Mom, Constantijne
A1 Chakalova,, Galina
A1 Shamistan, Aliyev
A1 Malzoni, Mario
A1 Narducci, Fabrice
A1 Arencibia, Octavio
A1 Raspagliesi, Francesco
A1 Toptas, Tayfun
A1 Cibula, David
A1 Kaidarova, Dilyara
A1 Meydanli, Mehmet Mutlu
A1 Tavares, Mariana
A1 Golub, Dmytro
A1 Perrone, Anna Myriam
A1 Poka, Robert
A1 Zusterzeel, Petra L M
A1 Aluloski, Igor
A1 Goffin, Frederic
A1 Haidopoulos, Dimitrios
A1 Haller, Herman
A1 Jach, Robert
A1 Yezhova, Iryna
A1 Bernardino, Margarida
A1 Bharathan, Rasiah
A1 Maenpaa, Minna M
A1 Sukhin, Vladyslav
A1 Feron, Jean-Guillaume
A1 Fruscio, Robert
A1 Kukk, Kersti
A1 Ponce, Jordi
A1 Demirkiran, Fuat
A1 Vorgias, George
A1 Povolotskaya, Natalia
A1 Coronado Martín, Pluvio J
A1 Marina, Tiermes
A1 Zapardiel, Ignacio
A1 Bizzarri, Nicolò
A1 Gorostidi, Mikel
A1 Gutierrez, Monica
A1 Manzour, Nabil
A1 Berasaluce, Arantxa
A1 Martin-Calvo, Nerea
A1 
YR 2022
UL http://ijgc.bmj.com/content/32/10/1236.abstract
AB Objective To evaluate whether compliance with European Society of Gynaecological Oncology (ESGO) surgery quality indicators impacts disease-free survival in patients undergoing radical hysterectomy for cervical cancer.Methods In this retrospective cohort study, 15 ESGO quality indicators were assessed in the SUCCOR database (patients who underwent radical hysterectomy for International Federation of Gynecology and Obstetrics (FIGO) stage 2009 IB1, FIGO 2018 IB1, and IB2 cervical cancer between January 2013 and December 2014), and the final score ranged between 0 and 16 points. Centers with more than 13 points were classified as high-quality indicator compliance centers. We constructed a weighted cohort using inverse probability weighting to adjust for the variables. We compared disease-free survival and overall survival using Cox proportional hazards regression analysis in the weighted cohort.Results A total of 838 patients were included in the study. The mean number of quality indicators compliance in this cohort was 13.6 (SD 1.45). A total of 479 (57.2%) patients were operated on at high compliance centers and 359 (42.8%) patients at low compliance centers. High compliance centers performed more open surgeries (58.4% vs 36.7%, p<0.01). Women who were operated on at centers with high compliance with quality indicators had a significantly lower risk of relapse (HR=0.39; 95% CI 0.25 to 0.61; p<0.001). The association was reduced, but remained significant, after further adjustment for conization, surgical approach, and use of manipulator surgery (HR=0.48; 95% CI 0.30 to 0.75; p=0.001) and adjustment for adjuvant therapy (HR=0.47; 95% CI 0.30 to 0.74; p=0.001). Risk of death from disease was significantly lower in women operated on at centers with high adherence to quality indicators (HR=0.43; 95% CI 0.19 to 0.97; p=0.041). However, the association was not significant after adjustment for conization, surgical approach, use of manipulator surgery, and adjuvant therapy.Conclusions Patients with early cervical cancer who underwent radical hysterectomy in centers with high compliance with ESGO quality indicators had a lower risk of recurrence and death.Data are available upon reasonable request.