PT  - JOURNAL ARTICLE
AU  - Ha-Jeong Kim
AU  - Tae-Joong Kim
AU  - Taejong Song
AU  - Min Kyu Kim
AU  - Yoo-Young Lee
AU  - Chel Hun Choi
AU  - Jeong-Won Lee
AU  - Duk-Soo Bae
AU  - Byoung-Gie Kim
TI  - Patterns of Recurrence in Endometrial Cancer Patients at Risk of Lymph Node Metastasis or Recurrence According to Extent of Lymphadenectomy
AID  - 10.1097/IGC.0b013e318249472d
DP  - 2012 May 01
TA  - International Journal of Gynecologic Cancer
PG  - 611--616
VI  - 22
IP  - 4
4099  - http://ijgc.bmj.com/content/22/4/611.short
4100  - http://ijgc.bmj.com/content/22/4/611.full
SO  - Int J Gynecol Cancer2012 May 01; 22
AB  - Objective The purpose of this study was to compare the patterns of recurrence in patients with risk of lymph node (LN) metastasis or recurrence according to the extent of lymphadenectomy (LND).Methods We selected 257 patients with risk of LN metastasis or recurrence who underwent definitive surgery as the first treatment between 1995 and 2009. These patients underwent hysterectomy, bilateral salpingo-oophorectomy, and systematic pelvic lymphadenectomy (PLND) with or without para-aortic lymphadenectomy (PALND). We identified patients with recurrence and evaluated the patterns of recurrence according to the type of LND.Results Among the 257 patients, 164 patients had systematic PLND only, and 93 patients had PLND with PALND. Regarding LN metastasis in PLND+PALND group, approximately 9.7% patients had involvement of para-aortic nodes. Thirty-six (14%) of the 257 patients showed recurrence. The rate of extrapelvic recurrence was significantly higher in the PLND group compared with the PLND+PALND group (96.0% vs 36.4%, respectively; P < 0.001). Using multivariate analysis, extent of LND was significantly related to extrapelvic recurrence (P = 0.004).Conclusions The incidence of extrapelvic recurrence was significantly higher in the PLND group than in the PLND+PALND group, which suggests that PALND decreases the risk of extrapelvic recurrence.