PT  - JOURNAL ARTICLE
AU  - Jacob McGee
AU  - Karen Panabaker
AU  - Sean Leonard
AU  - Peter Ainsworth
AU  - Laurie Elit
AU  - Salimah Z. Shariff
TI  - Genetics Consultation Rates Following a Diagnosis of High-Grade Serous Ovarian Carcinoma in the Canadian Province of Ontario
AID  - 10.1097/IGC.0000000000000907
DP  - 2017 Mar 01
TA  - International Journal of Gynecologic Cancer
PG  - 437--443
VI  - 27
IP  - 3
4099  - http://ijgc.bmj.com/content/27/3/437.short
4100  - http://ijgc.bmj.com/content/27/3/437.full
SO  - Int J Gynecol Cancer2017 Mar 01; 27
AB  - Objective In 2001, the province of Ontario expanded cancer genetic testing eligibility to include all women with high-grade serous ovarian carcinoma (HGSC) of the ovary, fallopian tube, and peritoneum. The aim of this study was to determine the proportion of women who attended genetics counseling for consideration of BRCA1/2 gene analysis. We also sought to examine if regional differences in consultation rate exist across administrative health regions in the province of Ontario.Methods We identified all women with a pathological diagnosis of HGSC in the province of Ontario between 1997 until 2011. Our primary outcome was the 2-year rate of genetics consultation following a diagnosis of HGSC. We compared consultation rates over time and geographical regions and applied multiple logistic regression to identify predictors of genetics consultation.Results Of the 5412 women with a diagnosis of HGSC over the study period, 6.6% were seen for genetics consultation within 2 years of diagnosis. Factors predictive of genetics consultation included history of breast cancer (odds ratio [OR], 3.56; 95% confidence interval [CI], 1.87–6.78), era of diagnosis (2009–2011 vs 1997–2000; OR, 10.59; 95% CI, 5.02–22.33), and younger age at diagnosis (OR, 0.95; 95% CI, 0.94–0.97 for each additional year). No regional differences in consultation rate were seen.Conclusions Despite an increasing rate across eras, a small proportion of women with HGSC undergo genetics consultation. Efforts are required to increase cancer genetics consultation in patients with HGSC in the province of Ontario.