RT Journal Article
SR Electronic
T1 Patterns of Care and Outcome of Elderly Women Diagnosed With Cervical Cancer in the Developing World
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP 1246
OP 1251
DO 10.1097/IGC.0000000000000756
VO 26
IS 7
A1 Angelica Nogueira-Rodrigues
A1 Andreia Cristina de Melo
A1 Alvaro Henrique Ingles Garces
A1 Eduardo Paulino
A1 Flavia Vieira Guerra Alves
A1 Mariana do Nascimento Vilaça
A1 Laisa Gabrielle Silva
A1 Cristiane Alves Gonçalves
A1 Juliana Chaves Fabrini
A1 Anderson Thiago Vieira Carneiro
A1 Luiz Claudio Santos Thuler
YR 2016
UL http://ijgc.bmj.com/content/26/7/1246.abstract
AB Abstract Scarce data exist about the impact of age in cervical cancer (CC) patients in the developing world. The objective of the current study was to examine the patterns of care and outcome of elderly patients treated in a developing country. Medical records of patients treated from 2006–2009 at the Brazilian National Cancer Institute were reviewed. Patients were divided between women 70 years or older and women younger than 70 years. The χ2 tests were used and odds ratios were calculated. Survival was examined using the Kaplan-Meier method. Single and multivariate Cox proportional hazards modeling were used. A total of 1482 patients were analyzed: 1339 patients younger than 70 years and 143 patients 70 years or older. A marked difference in treatment was noted, even after stratifying by disease stage. Only 21% of the older patients underwent surgical treatment compared with 27.6% of the younger. After adjusting for confounding variables, the hazard ratio for death from CC in the elderly was 1.05 (95% confidence interval, 0.81–1.36; P = 0.11). These results corroborate previous data from developed countries: elderly patients have more advanced disease at diagnosis, and age is an important factor in the allocation of treatment for patients with CC. Worse outcome seemed to be mainly the result of more advanced stage and treatment allocation rather than age itself.