RT Journal Article
SR Electronic
T1 Definitive chemoradiation or radiation therapy alone for the management of vulvar cancer
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP 332
OP 337
DO 10.1136/ijgc-2021-002530
VO 32
IS 3
A1 Parul Nafees Barry
A1 Diane C Ling
A1 Sushil Beriwal
YR 2022
UL http://ijgc.bmj.com/content/32/3/332.abstract
AB Vulvar cancer is rare, and unresectable disease provides a therapeutic conundrum. Although definitive surgery remains the mainstay for curative treatment of vulvar cancer, a minority of patients present with advanced disease for which surgical resection would be extraordinarily morbid. Pre-operative and definitive radiation with radiosensitizing systemic therapy allows such patients an opportunity for cure. In this review, we explore the origins of pre-operative radiation, current treatment standards for pre-operative and definitive chemoradiation, and future directions.