PT - JOURNAL ARTICLE AU - S Djanklich AU - Z Sabirdjanova TI - EPV286/#444 Trends in morbidity of vulvar cancer in Uzbekistan AID - 10.1136/ijgc-2021-IGCS.357 DP - 2021 Nov 01 TA - International Journal of Gynecologic Cancer PG - A142--A142 VI - 31 IP - Suppl 4 4099 - http://ijgc.bmj.com/content/31/Suppl_4/A142.1.short 4100 - http://ijgc.bmj.com/content/31/Suppl_4/A142.1.full SO - Int J Gynecol Cancer2021 Nov 01; 31 AB - Objectives To analyze trends in cancer morbidity for vulvar cancer (VC) in Uzbekistan.Methods We collected vulvar cancer incidence data from official statistics in Uzbekistan for the years 2017+2018.Results Totally 131 patients with VC have been registered, 61 in 2017 and 70 in 2018 of which rural women are 33, 40 and respectively. According to the age patients were registered as follows: in 2017 from 18 to 35 years old - 4 patients, from 36 to 55 years old - 14 patients, from 56 to 70 years old - 35 patients, older than 70 years old - 19 patients;in 2018 from the age of 18 up to 35 years old 1 patient, 36–55 years old - 20 patients, 56–70 years old - 24 patients and 16 patients are older than 70 years. In 2017, the largest number of VC patients ware registered in Tashkent (17), Kashkadarya (10), Bukhara (10) and Tashkent regions (8). In 2018, there was an increase in the number of VC patients in the Republic of Karakalpakstan (from 4 to 13), in the Khorezm region (from 5 to 9), while in Tashkent and the Tashkent region the number of registered cases of VC decreased (9 and 3, respectively). In 2018, the number of VC cases increased in Tashkent region, Tashkent and Namangan (10, 9 and 9 respectively). In Syrdarya, Jizzakh and Navoi regions in 2017–18 years there were no cases of VC.Conclusions Screening programs will allow timely diagnosis of vulvar background and precancerous diseases and reduce the number of patients with this pathology.