RT Journal Article
SR Electronic
T1 EPV207/#484 Disparate trends in ovarian cancer in Asians living in Asia and the United States
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP A111
OP A111
DO 10.1136/ijgc-2021-IGCS.278
VO 31
IS Suppl 4
A1 Liao, C-I
A1 Thayer, E
A1 Moon, A
A1 Wong, D
A1 Chan, A
A1 Milki, A
A1 Francoeur, A
A1 Chan, J
YR 2021
UL http://ijgc.bmj.com/content/31/Suppl_4/A111.2.abstract
AB Objectives To describe trends in ovarian cancer among native Asians and in the United States.Methods Data were obtained from the United States Cancer Statistics (USCS) and Taiwan Cancer Registry of Taiwan Health and Welfare Data Center from 2001 to 2017. SEER*Stat 8.3.9, Joinpoint regression program 4.8.0.1, and Excel were used to calculate incidences and trends.Results From 2001 to 2017, ovarian cancer incidence rose in native Asians (Taiwan) at a rate of 2.1% per year (p<0.001) while they fell in US Asians at 1.2% per year (p=0.026). Native Asians had increasing incidences of cancers of all cell types, with the fastest growth seen in rare ovarian tumors such as carcinosarcoma (6.4% per year, p=0.003), clear cell carcinoma (6.2% per year, p<0.001), and sex cord stromal (5.7% per year, p<0.001). Interestingly, although the overall incidence of ovarian cancer decreased in US Asians, the incidence of clear cell carcinoma rose 2.1% per year (p<0.001) in this group. In 2017, the peak age ovarian cancer in native Asians was 55–59 years old, younger than the peak in US Asians at 75–79 years old.Conclusions From 2001 to 2017 the ovarian cancer incidence in native Asians rose, driven by increases in rare tumors, while the incidence in Asians living in the US declined, leading to 25% more cancers among native Asians than US Asians.