TY - JOUR T1 - OP024/#182 Findings and outcomes in a post-vaccination cohort of young women under 25 years attending a tertiary colposcopy service JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - A21 LP - A21 DO - 10.1136/ijgc-2021-IGCS.41 VL - 31 IS - Suppl 4 AU - C Yim AU - Y Jayasinghe AU - D Wrede AU - J Tan Y1 - 2021/11/01 UR - http://ijgc.bmj.com/content/31/Suppl_4/A21.1.abstract N2 - Objectives In 2007, human papillomavirus (HPV) vaccination was rolled out in Australia, with a high uptake of 73%, and a consequent reduction in high-grade dysplasia in young women. The aim was to provide descriptive data on post-vaccination women below 25 years between 2008 and 2017, prior to the change in cervical screening guidelines.Methods A retrospective cohort analysis of women under 25 attending a tertiary colposcopy clinic.Results 3128 women with a median age of 22 (range 14–24) years were identified. When comparing overall worst histology result, vaccinated women were less likely to have a high grade abnormality than unvaccinated women (RR 0.78, 95%CI 0.67–0.90, p=0.0006). Amongst those with high grade abnormalities, there was no significant difference in rates of CIN2 or CIN3 between vaccinated and unvaccinated women (RR 0.81, 95%CI 0.62–1.05, p=0.1086).Conclusions This study provides baseline data on young women under the previous cervical screening program, following the introduction of the HPV vaccine. ER -