RT Journal Article SR Electronic T1 EPV249/#482 Racial disparities in the completion of the hpv vaccination series in women in the United States – a 9-year study JF International Journal of Gynecologic Cancer JO Int J Gynecol Cancer FD BMJ Publishing Group Ltd SP A127 OP A127 DO 10.1136/ijgc-2021-IGCS.320 VO 31 IS Suppl 4 A1 C-I Liao A1 A Milki A1 D Wong A1 E Thayer A1 A Moon A1 A Chan A1 A Francoeur A1 J Chan YR 2021 UL http://ijgc.bmj.com/content/31/Suppl_4/A127.2.abstract AB Objectives To identify disparities and trends in HPV vaccination status and trends across races.Methods HPV vaccination rates were evaluated using the Behavioral Risk Factor Surveillance System (BRFSS). Joinpoint regression program 4.8.0.1 was used to calculate the trend (average annual percent change, AAPC).Results In all patients, there was an increase in 3-dose vaccination from 2008 to 2016 (3.6% annual percent change (APC), p=0.042). There was also an increase in APC of 19.4% between 2008 and 2010 (p=0.046). When examining only those between 18–24 years of age, there was an APC of 26% (p=0.037). From 2010 to 2016, there was no significant APC in all age groups assessed. In 2008, 27.78% of Blacks, 25% of Hispanics, 48.78% of Whites, and 42.86% of Asians had received 3 vaccine doses. In 18 to 24 year old Black patients, there was an APC of 77.3% from 2008 to 2010 (p=0.027), followed by a -7.4% APC (p=0.053) from 2010 to 2016. Hispanic patients also showed a significant increase in vaccine completion; a 43.9% APC took place from 2008 to 2010 (p=0.040) among 18–24-year-old patients, and a 39.7% in APC took place in the total Hispanic population (p=0.033).Conclusions The majority of the increase in 3-dose vaccination that took place across all races from 2008 to 2016 took place in the first 3 years of that time period. Black and Hispanic patients were least likely to have 3 doses of the HPV vaccine in 2008, but experienced the greatest increases in rates of vaccine completion between 2008 and 2010.