RT Journal Article SR Electronic T1 EPV044/#201 Understanding the never-screened population for cervical cancer in the United States – a descriptive and trend analysis JF International Journal of Gynecologic Cancer JO Int J Gynecol Cancer FD BMJ Publishing Group Ltd SP A46 OP A47 DO 10.1136/ijgc-2021-IGCS.112 VO 31 IS Suppl 4 A1 A Francoeur A1 C-I Liao A1 D Wong A1 E Thayer A1 A Milki A1 A Moon A1 A Mann A1 MA Caesar A1 A Chan A1 D Kapp A1 B Monk A1 J Chan YR 2021 UL http://ijgc.bmj.com/content/31/Suppl_4/A46.3.abstract AB Objectives It is estimated that 50% of patients diagnosed with cervical cancer never had any screening. We aimed to determine the changes in cervical cancer screening in the United States.Methods Pap smear rates were evaluated using the Behavioral Risk Factor Surveillance System (BRFSS). SEER*Stat 8.3.8 and Joinpoint regression program 4.8.0.1 were used to calculate incidence trends.Results In 2016, 6.28% women in the U.S were never screened for cervical cancer. Based on race, 21.3% of Asian, 11.63% Hispanic, 8.09% Black and 5.1% of White women have never undergone screening. The age groups with higher never screened rates were the 80 and older age cohort at 11.14% followed by the 25–29 group at 8.87%. Over the last 6 years of our study, there has been an increase of 7.4% annually of never screened rates (p=0.008). In regards to age, there has been an increase in never pap was the 25–29 age group (AAPC +7.31%, p<0.001). White and Black women have increasing never pap smear rates at 1.49% (p=0.008) and 4.05% (p<0.001), respectively, while Hispanic women have no change. The intersectionality of age and race shows that Black women ages 25–29 have the highest increased rate of no screening, 9.84% annually (p<0.001).Conclusions Based on this large survey, nearly one fourth of Asian women were never screened for cervical cancer in the U.S. There is also an increasing proportion of never-screened particularly in younger Black women. Further research is warranted to understand the change in screening practices in relation to vaccination and access to care.