@article {HAGMAR341, author = {B. HAGMAR and J.-J. P. CHRISTENSEN and B. JOHANSSON and M. KALANTARI and W. RYD and B. SKYLDBERG and L. WALAAS and B. W{\"A}RLEBY and G. B. KRISTENSEN}, title = {Implications of human papillomavirus type for survival in cervical squamous cell carcinoma}, volume = {5}, number = {5}, pages = {341--345}, year = {1995}, doi = {10.1046/j.1525-1438.1995.05050341.x}, publisher = {BMJ Specialist Journals}, abstract = {In a Swedish series of 107 invasive squamous carcinomas of the cervix, DNA extraction from paraffin-embedded material was successful in 97 cases. The prevalence of human papillomavirus (HPV) in this material was 86.6\%, as determined by polymerase chain reaction (PCR) using both consensus and type-specific primers. HPV type 16 was most common (42.3\%; other types were 31 (12.3\%), 18 (9.3\%) and 33 (10.3\%). Seventeen cases (17.3\%) were positive for the consensus primers only and were regarded as HPV of unknown type. There was no significant difference in corrected survival between patients with HPV-positive or -negative tumors. In the HPV-positive group, patients with tumors containing HPV 33 or HPV 18 had a significantly poorer prognosis than patients with tumors containing other types of HPV DNA (relative hazard 3.18, 95\% confidence interval 1.37{\textendash}7.39, P = 0.007), implying a prognostic significance of HPV type.}, issn = {1048-891X}, URL = {https://ijgc.bmj.com/content/5/5/341}, eprint = {https://ijgc.bmj.com/content/5/5/341.full.pdf}, journal = {International Journal of Gynecologic Cancer} }