TY - JOUR T1 - 1182 Resection of the upper paracervical lymphovascular tissue should be a part of a pelvic sentinel lymph node algorithm in early stage cervical cancer JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - A365 LP - A365 DO - 10.1136/ijgc-2021-ESGO.643 VL - 31 IS - Suppl 3 AU - O Lührs AU - L Ekdahl AU - B Geppert AU - C Lönnerfors AU - J Persson Y1 - 2021/10/01 UR - http://ijgc.bmj.com/content/31/Suppl_3/A365.abstract N2 - Introduction/Background*To investigate the prevalence of lymph nodes and lymph node metastases (LNMs) in the upper paracervical lymphovascular tissue (UPLT) in early stage cervical cancer.Methodology In this prospective study consecutive women with stage IA1-IB1 cervical cancer underwent a pelvic lymphadenectomy including identification of sentinel nodes (SLNs) as part of a nodal staging procedure in conjunction with a robotic radical hysterectomy (RRH) or robotic radical trachelectomy (RRT). Indocyanine green (ICG) was used as tracer. The UPLT was separately removed and defined as “SLN-parametrium” and, as all SLN tissue, subjected to ultrastaging and immunohistochemistry. Primary endpoint was prevalence of lymph nodes and metastatic lymph nodes in the UPLT. Secondary endpoints were complications associated with removal of the UPLT.Result(s)*One hundred and forty-five women were analysed. Nineteen (13.1%) had pelvic LNMs, all identified by at least one metastatic SLN. In 76 women (52.4%) at least one UPLT lymph node was identified. Metastatic UPLT lymph nodes were identified in six women of which in three women (2.1% of all women and 15.8% of node positive women) without lateral pelvic LNMs. Thirteen women had lateral pelvic SLN LNMs with either no (n=5) or benign (n=8) UPLT lymph nodes. No intraoperative complications occurred due to the removal of the UPLT.Conclusion*Removal of the UPLT should be an integral part of the SLN concept in early stage cervical cancer. ER -