TY - JOUR T1 - Radical hysterectomy in early cervical cancer in Europe: characteristics, outcomes and evaluation of ESGO quality indicators JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - 1212 LP - 1219 DO - 10.1136/ijgc-2021-002587 VL - 31 IS - 9 AU - Felix Boria AU - Luis Chiva AU - Vanna Zanagnolo AU - Denis Querleu AU - Nerea Martin-Calvo AU - Mihai Emil Căpîlna AU - Anna Fagotti AU - Ali Kucukmetin AU - Constantijne Mom AU - Galina Chakalova, AU - Aliyev Shamistan AU - Mario Malzoni AU - Fabrice Narducci AU - Octavio Arencibia AU - Francesco Raspagliesi AU - Tayfun Toptas AU - David Cibula AU - Dilyara Kaidarova AU - Mehmet Mutlu Meydanli AU - Mariana Tavares AU - Dmytro Golub AU - Anna Myriam Perrone AU - Robert Poka AU - Dimitrios Tsolakidis AU - Goran Vujić AU - Marcin A Jedryka AU - Petra L M Zusterzeel AU - Jogchum Jan Beltman AU - Frederic Goffin AU - Dimitrios Haidopoulos AU - Herman Haller AU - Robert Jach AU - Iryna Yezhova AU - Igor Berlev AU - Margarida Bernardino AU - Rasiah Bharathan AU - Maximilian Lanner AU - Minna M Maenpaa AU - Vladyslav Sukhin AU - Jean-Guillaume Feron AU - Robert Fruscio AU - Kersti Kukk AU - Jordi Ponce AU - María Alonso-Espías AU - Jose Angel Minguez AU - Daniel Vázquez-Vicente AU - Nabil Manzour AU - Matias Jurado AU - Teresa Castellanos AU - Enrique Chacon AU - Juan Luis Alcazar Y1 - 2021/09/01 UR - http://ijgc.bmj.com/content/31/9/1212.abstract N2 - Introduction Comprehensive updated information on cervical cancer surgical treatment in Europe is scarce.Objective To evaluate baseline characteristics of women with early cervical cancer and to analyze the outcomes of the ESGO quality indicators after radical hysterectomy in the SUCCOR database.Methods The SUCCOR database consisted of 1272 patients who underwent radical hysterectomy for stage IB1 cervical cancer (FIGO 2009) between January 2013 and December 2014. After exclusion criteria, the final sample included 1156 patients. This study first described the clinical, surgical, pathological, and follow-up variables of this population and then analyzed the outcomes (disease-free survival and overall survival) after radical hysterectomy. Surgical-related ESGO quality indicators were assessed and the accomplishment of the stated recommendations was verified.Results The mean age of the patients was 47.1 years (SD 10.8), with a mean body mass index of 25.4 kg/m2 (SD 4.9). A total of 423 (36.6%) patients had a previous cone biopsy. Tumor size (clinical examination) <2 cm was observed in 667 (57.7%) patients. The most frequent histology type was squamous carcinoma (794 (68.7%) patients), and positive lymph nodes were found in 143 (12.4%) patients. A total of 633 (54.8%) patients were operated by open abdominal surgery. Intra-operative complications occurred in 108 (9.3%) patients, and post-operative complications during the first month occurred in 249 (21.5%) patients, with bladder dysfunction as the most frequent event (119 (10.3%) patients). Clavien-Dindo grade III or higher complication occurred in 56 (4.8%) patients. A total of 510 (44.1%) patients received adjuvant therapy. After a median follow-up of 58 months (range 0–84), the 5-year disease-free survival was 88.3%, and the overall survival was 94.9%. In our population, 10 of the 11 surgical-related quality indicators currently recommended by ESGO were fully fulfilled 5 years before its implementation.Conclusions In this European cohort, the rate of adjuvant therapy after radical hysterectomy is higher than for most similar patients reported in the literature. The majority of centers were already following the European recommendations even 5 years prior to the ESGO quality indicator implementations.All data relevant to the study are included in the article or uploaded as supplementary information. Data will be available upon the requirement of the reviewers at any time. ER -