RT Journal Article
SR Electronic
T1 Fertility preservation in patients with BRCA mutations or Lynch syndrome
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP 332
OP 338
DO 10.1136/ijgc-2020-002071
VO 31
IS 3
A1 Giacomo Corrado
A1 Claudia Marchetti
A1 Rita Trozzi
A1 Giovanni Scambia
A1 Anna Fagotti
YR 2021
UL http://ijgc.bmj.com/content/31/3/332.abstract
AB Guidelines and expert consensus are lacking on fertility preservation in BRCA mutation carriers and in patients with Lynch syndrome. The safety of fertility preservation in this setting is still a topic of debate and multiple factors need to be carefully considered. The aim of this review was to analyze the reproductive potential of women harboring a genetic mutation affecting the DNA repair system and explore the efficacy and safety of existing fertility preservation strategies in these patients.