PT  - JOURNAL ARTICLE
AU  - J. DUPONT
AU  - C. AGHAJANIAN
AU  - P. SABBATINI
AU  - D. R. SPRIGGS
TI  - New agents for the treatment of ovarian cancer: the next generation
AID  - 10.1136/ijgc-00009577-200511001-00012
DP  - 2005 Nov 01
TA  - International Journal of Gynecologic Cancer
PG  - 252--257
VI  - 15
IP  - Suppl 3
4099  - http://ijgc.bmj.com/content/15/Suppl_3/252.short
4100  - http://ijgc.bmj.com/content/15/Suppl_3/252.full
SO  - Int J Gynecol Cancer2005 Nov 01; 15
AB  - Ovarian cancer shares many important characteristics with more common malignancies including breast, lung, and colon cancer. The relative chemosensitivity of ovarian cancer and other aspects of its unique biology provide opportunities for novel interventions. In this brief summary, some of the potential targets in ovarian cancer are discussed, including the HER kinases, heat shock protein, the 26S proteasome, and the angiogenesis pathway. The opportunities to change the treatment of ovarian cancer will require creative clinical trial design but the next decade promises to be filled the therapeutic advances for patients with ovarian cancer.