TY - JOUR T1 - 389 Papillary carcinoma in the breast of the male : Report of 3 cases JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - A162 LP - A162 DO - 10.1136/ijgc-2020-IGCS.336 VL - 30 IS - Suppl 3 AU - I Bouraoui AU - M Bouhani AU - M Slimene AU - S Sakhri AU - O Adouni AU - M Hechiche AU - R Chargui AU - K Rahal Y1 - 2020/11/01 UR - http://ijgc.bmj.com/content/30/Suppl_3/A162.1.abstract N2 - Introduction Breast cancer of male is a rare disease that accounts for less then 1.5% of all malignancies in men. Similar to women, invasive ductual carcinoma is the most common subtype while papillary carcinoma remains an extremely rare entity in men representing 5 to 7.5% of all breast male carcinomas. It is defined as a tumor that develops from the wall of a cyst in the breast and it can be in situ or invasive carcinoma.Methods We reviewed retrospectively 70 cases of papillary carcinoma at salah Azaiez institute between 2003 and 2019. Three of them were intracystic papillary carcinoma in men.Results The mean age was 75 years old. Physical findings noted painless mass in all patients. Right breast was the most involved with predominantly retroareolar lesion. Mean tumor size was 26 mm. Palpable axillary lymph nodes was detected in one patient. Ultrasound examination revealed intracystic tumour in all patients. Diagnosis was made by core needle biopsy.Two patients underwent mastectomy with axillary lymph node dissection while the third one had lympectomy under local anesthesia. Histological analysis showed intracystic papillary carcinoma in all patients. Immunohistochemical study marked the positivity of hormonal receptor and negativity of HER in all cases. Adjuvant radiotherapy was indicated for all patients and tamoxifen was administrated in all patients. The mean follow up period was 50 months and no local recurrence or distant metastasis was noted.Conclusion Intracystic Papillary carcinoma has a good prognosis with benign presentation looking a cystic lesion. ER -