PT  - JOURNAL ARTICLE
AU  - T. Meyer
AU  - R. Arndt
AU  - E.-R. Beckmann
AU  - B. Padberg
AU  - E. Christophers
AU  - E. Stockfleth
TI  - Distribution of HPV 53, HPV 73 and CP8304 in genital epithelial lesions with different grades of dysplasia
AID  - 10.1136/ijgc-00009577-200105000-00006
DP  - 2001 May 01
TA  - International Journal of Gynecologic Cancer
PG  - 198--204
VI  - 11
IP  - 3
4099  - http://ijgc.bmj.com/content/11/3/198.short
4100  - http://ijgc.bmj.com/content/11/3/198.full
SO  - Int J Gynecol Cancer2001 May 01; 11
AB  - To characterize the risk of malignant progression of cervical epithelial lesions associated with human papillomavirus (HPV) types of yet unknown oncogenic potential the prevalences of these HPVs in different cervical epithelial lesions of 809 patients were determined. HPV types 53, 73, and CP8304 were detected in genital specimens of 16, 22, and 12 of the patients, respectively. The ratio of prevalence in high grade dysplastic lesions or cancers and low grade dysplastic lesions or normal specimens was calculated and compared to corresponding values of well known high-risk (HR) and low-risk (LR) HPVs. For HPV 6, 11, 16, 18, 35, and 73 a ratio of 0.1, 0.2, 5.9, 6.5, 2.5, and 2.4, respectively, was calculated. The ratios of HPV53 and CP8304 were less than 1. Moreover, in contrast to HPV73, these viruses have never been detected in cancer specimens. Thus, HPV53 and CP8304 infections are probably not associated with a high risk of carcinogenesis, while HPV73 could be another HR-HPV type.