TY - JOUR T1 - Placental site trophoblastic tumor presenting with scalp metastases JF - International Journal of Gynecologic Cancer JO - Int J Gynecol Cancer SP - 333 LP - 336 DO - 10.1136/ijgc-00009577-199607000-00016 VL - 6 IS - 4 AU - E.M. Hartenbach AU - A.K. Saltzman AU - C. B. Zachary AU - J.L. Osborne AU - T. Okagaki AU - L.B. Twiggs Y1 - 1996/07/01 UR - http://ijgc.bmj.com/content/6/4/333.abstract N2 - Placental site trophoblastic tumor (PSTT) usually presents with vaginal bleeding or amenorrhea and an enlarged uterus. Metastasis to the skin as the presenting sign, or as a metastatic site, has not been previously reported with PSTT. We report a case of PSTT in which the presenting sign was scalp metastases and the only other disease was a small focus in the uterus. The patient responded to multi-agent chemotherapy and repeated skin resection at the local site. She received 16 alternating cycles of etoposide-methotrexate-actinomycin D and cytoxan-oncovin (EMA/CO) and is currently without evidence of disease. Clinicians caring for reproductive age women should remain aware that gestational trophoblastic disease (GTD) may present in an unusual manner. ER -