RT Journal Article
SR Electronic
T1 EP897 Clinical application of the sentinel lymph node technique in early ovarian cancer: phase II clinical trial
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP A485
OP A485
DO 10.1136/ijgc-2019-ESGO.944
VO 29
IS Suppl 4
A1 Lago, V
A1 Bello, P
A1 Montero, B
A1 Matute, L
A1 Padilla-Iserte, P
A1 Lopez, S
A1 Agudelo, M
A1 Domingo, S
YR 2019
UL http://ijgc.bmj.com/content/29/Suppl_4/A485.1.abstract
AB Introduction/Background There is limited evidence favoring the use of the sentinel lymph node technique in ovarian cancer, and no standardized approach has been studied. The objective of the present pilot study and clinical trial is to determine the feasibility of the sentinel lymph node technique by applying a clinical algorithm and the use of 99mTc and indocyanine green for its detection.Methodology Patients with confirmed ovarian cancer were included. 99mTc and indocyanine green were injected into the ovarian and infundubulo-pelvic ligament stump.A gamma probe and near-infrared fluorescence imaging were used for sentinel lymph node detection.Results The sentinel lymph node technique was performed in 10 patients in the pilot study and in 20 patients in the clinical trial with a detection rate in the pelvic and/or para-aortic region of 100%.Conclusion The sentinel lymph node technique appears to be applicable in early-stage ovarian cancer with excellent detection rate. further studies are needed to establish the negative predictive value of the technique.Disclosure Nothing to disclose.