PT  - JOURNAL ARTICLE
AU  - A Vazquez Sarandeses
AU  - M Hernandez Ontoria
AU  - G Lopez Garcia
AU  - A Tejerizo Garcia
TI  - EP426 Predictive value of the sentinel lymph node biopsy (SLNB) in early-stage cervical cancer: is pelvic lymphadenectomy replaceable?
AID  - 10.1136/ijgc-2019-ESGO.485
DP  - 2019 Nov 01
TA  - International Journal of Gynecologic Cancer
PG  - A277--A277
VI  - 29
IP  - Suppl 4
4099  - http://ijgc.bmj.com/content/29/Suppl_4/A277.1.short
4100  - http://ijgc.bmj.com/content/29/Suppl_4/A277.1.full
SO  - Int J Gynecol Cancer2019 Nov 01; 29
AB  - Introduction/Background We analyzed the predictive value of the Sentinel Lymph Node Biopsy (SLNB) in order to assess its safety and reliability.Methodology Retrospective analyses of patients diagnosed with early-stage cervical cancer (ESCC) between June 2010 and June 2017. All patients underwent SLNB followed by pelvic lymphadenectomy (PL). Stage was IA1 to IIA1.Results 61(39,8%) met the inclusion criteria. The mean tumor size was 21.1 mm preoperatively. A 70% of the patients had a tumor size ≤2 cm. We performed 47 (77.0%) SLNB followed by bilateral PL. According to the technique we obtained bilateral detection in 30/47 patients (63,8%). Unilateral detection was observed in 12/47 cases (25,5%) and bilateral failure in 5/47 cases (10.6%). The lymph node status was positive in 4/47 cases (8.5%) in which para-aortic lymphadenectomy was accomplished for staging.The overall detection rate of the technique was 76.6%. We found a sensitivity of 100%, a specificity of 75,5%, a negative predictive value of 100% and a false negative rate of 0%.We observed a lymphovascular and neurological morbidity in 6.4% (3/47), and 8.5% (4/47) respectively.Conclusion The SLNB would allow a decrease in the morbidity associated with PL.It seems to be a trend towards a more conservative and less aggressive surgery.Accurate selection of patients is key point.Disclosure Nothing to disclose.View this table:Abstract EP426 Table 1 Patients’ and tumor characteristics