@article {ReillyA88, author = {K Reilly and E Craig and H Nagar and S Dobbs and M McComiskey and I Harley}, title = {201 Laparoscopic extra-peritoneal para-aortic node dissections in the belfast trust over the last 9 years: a single institution experience for locally advanced cervical carcinoma}, volume = {29}, number = {Suppl 3}, pages = {A88--A89}, year = {2019}, doi = {10.1136/ijgc-2019-IGCS.201}, publisher = {BMJ Specialist Journals}, abstract = {Objectives Cervical cancer is one of the most commonly occurring female cancers with increasing incidence. The mainstay of treatment for locally advanced disease is primary chemoradiotherapy. Pre-operative imaging in combination with laparoscopic extraperitoneal para-aortic node dissection (LEPAND) has been used to best target this treatment. This study looked at all women in the Belfast Trust over the last 9 years who had this investigation as part of their pre-treatment workup.Methods Retrospective data was collected for all those who had LEPAND for locally advanced cervical cancer from January 2010 to December 2018. All women had pre-operative imaging that suggested positive pelvic nodes but negative para-aortic nodes.Results Sixty women were identified in this group ageing 23{\textendash}69 with median age 39. 93.3\% had stage 2b cervical cancer, the remainder were 1b2 or 3b. 17\% had adenocarcinoma of the cervix and 83\% had squamous cell carcinoma. The median survival overall is 5 years. 70\% of women had primary LEPAND surgery before chemoradiotherapy with the remainder having primary treatment before surgery. 15\% of the study population died, 90\% of which died within two years of diagnosis. 67\% of these women had primary LEPAND followed by chemoradiotherapy with the others proceeding straight to primary treatment prior to surgery. 5\% (3/60) had positive para-aortic nodes on histopathology although 100\% appeared node negative on MRI/PET imaging. None with positive nodes had recurrences but 66\% died within 2 years.Conclusions Despite having negative nodes on imaging 5\% had positive para-aortic lymph nodes on histopathology. LEPAND surgery prevented undertreatment in these women.}, issn = {1048-891X}, URL = {https://ijgc.bmj.com/content/29/Suppl_3/A88.3}, eprint = {https://ijgc.bmj.com/content/29/Suppl_3/A88.3.full.pdf}, journal = {International Journal of Gynecologic Cancer} }