PT - JOURNAL ARTICLE AU - C Fitzsimmons AU - A Stephens AU - J Kennard AU - M Manyam AU - J Pepe AU - K DeCoff AU - S Ahmad AU - N McKenzie AU - J Kendrick AU - R Holloway TI - 169 Robotic radical hysterectomy (RRH) versus chemo-radiation (CRT) followed by type 1 robotic hysterectomy for 1B2 cervical cancer (CC) AID - 10.1136/ijgc-2019-IGCS.169 DP - 2019 Sep 01 TA - International Journal of Gynecologic Cancer PG - A76--A76 VI - 29 IP - Suppl 3 4099 - http://ijgc.bmj.com/content/29/Suppl_3/A76.2.short 4100 - http://ijgc.bmj.com/content/29/Suppl_3/A76.2.full SO - Int J Gynecol Cancer2019 Sep 01; 29 AB - Objectives To compare peri-operative outcomes, RFS, and OS for patients with FIGO-2014 stage 1B2 CC treated by RRH versus CRT and brachytherapy (BT) followed by Type 1 robotic hysterectomy (RH).Methods Patients with FIGO-2014 stage 1B2 CC (1/2007–12/2017) who underwent RRH (Group A) or CRT and VB followed by RH (Group B) were identified. Inclusion criteria included: adenocarcinoma or squamous cell histology; >12 month follow-up, tumor size (TS) >4 cm by either pathology in A or radiographic/clinical criteria in B, and no evidence of para-aortic node metastasis on imaging.Results 15 group A (median TS=5.0±1.2 cm) and 31 group B (median TS=5.0±1.0 cm) pts were identified. Pre-operative imaging reported no positive nodes in A compared to 8 (25%) in B. 12(80%) required adjuvant CRT in group A. Median follow-up time was 64±34.6 months for A versus 33±32.7 months for B (p=0.059). No (+) para-aortic nodes were identified in A versus 5 cases in B (p=0.15). Recurrences were diagnosed in 3 (20%) A and 7 (22.5%) B cases. Median time to recurrence was 15.0±49 months for A compared to 11.0±7 months in B. 5-year RFS and OS was 80% & 84.7% (A) versus 78% & 83.9% (B). Complications included urinary fistula (n=3; 20%) and cuff dehiscence (n=1; 6.7%) in A versus one each for B (3.3%).View this table:Abstract 169 Table 1 Conclusions Despite having higher risk factors including para-aortic metastasis, patients with IB2 CC treated with CRT/BT/RH had similar RFS/OS to RRH, and with less fistulae and cuff dehiscence.