RT Journal Article
SR Electronic
T1 394 Sentinel lymph node mapping vs systematic lymphadenectomy for endometrial cancer: surgical morbidity and lymphatic complications
JF International Journal of Gynecologic Cancer
JO Int J Gynecol Cancer
FD BMJ Publishing Group Ltd
SP A162
OP A164
DO 10.1136/ijgc-2019-IGCS.394
VO 29
IS Suppl 3
A1 G Accorsi
A1 R dos Reis
A1 R Schmidt
A1 L Lacerda
A1 M Vieira
A1 C Andrade
YR 2019
UL http://ijgc.bmj.com/content/29/Suppl_3/A162.3.abstract
AB Objectives Sentinel lymph node (SLN) mappinghas been proven to accurately stage endometrial cancer (EC). However, there is a lack of studies comparing the incidence of complications between different lymph node approaches in EC. Our objective is to define the complication rates of SLN biopsy in EC patients.Methods We retrospectively analyzed all patients with EC surgically treated at Barretos Cancer Hospital between April 2013 and March 2018. We evaluated intraoperative complications and 30-day complications using the Memorial Sloan Lettering Cancer Center’s Surgical Secondary Events Grading System, separating the patients into four groups: hysterectomy (HT); hysterectomy plus pelvic lymphadenectomy, with or without para-aortic dissection (HT+LND); hysterectomy plus sentinel biopsy (HT+SLN); and hysterectomy plus lymphadenectomy and sentinel biopsy (HT+SLN+LND).Results As compared with the HT group, the HT+SLN group did not show any increased risk of complications in terms of intraoperative injury (0vs1; p=1.0) and 30-day complications (8vs7; p=0.782).The HT+LND group had an increased surgical time (370 min, p<0.001), greater intraoperative blood loss (100cc, p<0.001), and a higher incidence of injury during surgery (7%, p=0.005) and any 30-day complication (38.2%, p=0.002) as compared with HT+SLN. Performing LND was associated with a greater risk of 30-day complications (hazard ratio [HR]:14.25; 95% confidence interval [CI]:1.85–19.63) and intraoperative injury (HR:3.11; 95% CI:1.62–5.98).View this table:Abstract 394 Table 1 View this table:Abstract 394 Table 2 View this table:Abstract 394 Table 3 Conclusions SLN mapping does not increase morbidity in the surgical treatment of EC patients, and compared with comprehensive lymphadenectomy, it has a lower risk of complications. Our findings support the use of the SLN algorithm in EC patients.