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Sleep and gynecological cancer outcomes: opportunities to improve quality of life and survival
  1. Caroline Zhao1,
  2. Allison Grubbs1 and
  3. Emma L Barber1,2
  1. 1Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
  2. 2Institute for Public Health in Medicine, Chicago, Illinois, USA
  1. Correspondence to Dr Emma L Barber, Northwestern University, Evanston, USA; emma.barber{at}


Sleep is important for immune function, metabolic function and physical repair. Sleep is more commonly disrupted in women compared with men and is disrupted by surgery, chemotherapy, and cancer itself, making gynecological oncology patients at higher risk of insomnia and sleep disruption. Insomnia and sleep disruption are linked to increased pain, poorer quality of life, depression, and anxiety which can all negatively affect patient outcomes. A number of environmental, behavioral, and pharmacological interventions have been investigated to improve patient sleep and aid in the recovery process. It is vital to understand and address patient sleep quality in order to give patients the highest quality care and improve outcomes.

  • Gynecologic Surgical Procedures
  • Ovarian Cancer
  • Surgical Oncology
  • Postoperative Period
  • Uterine Cancer

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  • Contributors CZ, AG, and ELB conceived of the idea. CZ performed the literature review and designed the figures. All three authors worked on the manuscript. ELB and AG directed the project.

  • Funding ELB is supported by NICHD (K12 HD050121-12), the NIA (P30AG059988-01A1), and the GOG Foundation.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.