A randomized double-blind phase II study evaluating the role of maintenance therapy with cabozantinib in high-grade uterine sarcoma after stabilization or response to doxorubicin ± ifosfamide following surgery or in metastatic first line treatment (EORTC62113)

Isabelle Ray-Coquard; Helen Hatcher; Emmanuelle Bompas; Antonio Casado; Annekke Westermann; Nicolas Isambert; Paolo Giovanni Casali; Sarah Pratap; Daniel Stark; Claudia Valverde; Anjana Anand; Manon Huizing; Anne Floquet; Lars Lindner; Barbara Hermes; Beatrice Seddon; Corneel Coens; Robin Jones; Nick Reed

doi:10.1136/ijgc-2020-001519

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A randomized double-blind phase II study evaluating the role of maintenance therapy with cabozantinib in high-grade uterine sarcoma after stabilization or response to doxorubicin ± ifosfamide following surgery or in metastatic first line treatment (EORTC62113)

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Isabelle Ray-Coquard Centre Leon Berard, Lyon, Rhône-Alpes, FranceOncology, Université Claude Bernard Lyon 1, Villeurbanne, Auvergne-Rhône-Alpes, France PubMed articles Google scholar articles
Helen Hatcher medical oncology, Cambridge University, Cambridge, Cambridgeshire, UK PubMed articles Google scholar articles
Emmanuelle Bompas Medical Oncology Department, ICO, Saint Herblain, Pays de la Loire, France PubMed articles Google scholar articles
Antonio Casado Medical Oncology Department, Complutense University of Madrid, Madrid, Comunidad de Madrid, Spain PubMed articles Google scholar articles
Annekke Westermann Medical Oncology Department, Academisch Medisch Centrum, Amsterdam, North Holland, The Netherlands PubMed articles Google scholar articles
Nicolas Isambert Medical Oncology Department, Centre Georges-François Leclerc, Dijon, Bourgogne-Franche-Comté, France PubMed articles Google scholar articles
Paolo Giovanni Casali Medical Oncology Department, IRCCS, Milano, Lombardia, Italy PubMed articles Google scholar articles
Sarah Pratap Medical Oncology Department, Oxford University, Oxford, Oxfordshire, UK PubMed articles Google scholar articles
Daniel Stark Medical Oncology Department, Leeds Teaching Hospitals NHS Trust, Leeds, Leeds, UK PubMed articles Google scholar articles
Claudia Valverde Medical Oncology Department, Vall d'Hebron Hospital, Barcelona, Catalunya, Spain PubMed articles Google scholar articles
Anjana Anand Medical Oncology Department, Nottingham Trent University, Nottingham, Nottinghamshire, UK PubMed articles Google scholar articles
Manon Huizing Medical Oncology Department, Universitair Ziekenhuis Antwerpen, Edegem, Antwerp, Belgium PubMed articles Google scholar articles
Anne Floquet Medical Oncology Department, Institut Bergonié, Bordeaux, Aquitaine, France PubMed articles Google scholar articles
Lars Lindner Medical Oncology Department, Ludwig-Maximilians-Universitat Munchen, Munchen, Bayern, Germany PubMed articles Google scholar articles
Barbara Hermes Medical Oncology Department, Eberhard Karls Universitat Tubingen, Tubingen, Baden-Württemberg, Germany PubMed articles Google scholar articles
Beatrice Seddon Medical Oncology Department, University College London, London, London, UK PubMed articles Google scholar articles
Corneel Coens Statistics and Quality of Life, EORTC, Brussels, Belgium PubMed articles Google scholar articles
Robin Jones Medical Oncology, Royal Marsden Hospital NHS Trust, London, London, UK PubMed articles Google scholar articles
Nick Reed Medical Oncology, NHS Greater Glasgow and Clyde, Glasgow, Glasgow, UK PubMed articles Google scholar articles

Correspondence to Professor Isabelle Ray-Coquard, Centre Leon Berard, Lyon, Rhône-Alpes, France; isabelle.ray-coquard{at}lyon.unicancer.fr

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Ray-Coquard I, Hatcher H, Bompas E, et al

International Journal of Gynecologic Cancer Published Online First: 15 June 2020. doi: 10.1136/ijgc-2020-001519

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Accepted May 8, 2020
First published June 15, 2020.

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