TP53 mutations in high grade serous ovarian cancer and impact on clinical outcomes: a comparison of next generation sequencing and bioinformatics analyses

Victoria Mandilaras; Swati Garg; Michael Cabanero; Qian Tan; Chiara Pastrello; Julia Burnier; Katherine Karakasis; Lisa Wang; Neesha C Dhani; Marcus O Butler; Philippe L Bedard; Lillian L Siu; Blaise Clarke; Patricia Ann Shaw; Tracy Stockley; Igor Jurisica; Amit M Oza; Stephanie Lheureux

doi:10.1136/ijgc-2018-000087

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TP53 mutations in high grade serous ovarian cancer and impact on clinical outcomes: a comparison of next generation sequencing and bioinformatics analyses

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Victoria Mandilaras Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Swati Garg Advanced Molecular Diagnostics Laboratory, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Michael Cabanero Department of Laboratory Medicine and Pathology, University Health Network, Toronto, Ontario, Canada PubMed articles Google scholar articles
Qian Tan Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Chiara Pastrello Krembil Research Institute, University Health Network, Toronto, Ontario, Canada PubMed articles Google scholar articles
Julia Burnier Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Katherine Karakasis Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Lisa Wang Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Neesha C Dhani Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Marcus O Butler Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Philippe L Bedard Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Lillian L Siu Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Blaise Clarke Department of Laboratory Medicine and Pathology, University Health Network, Toronto, Ontario, Canada PubMed articles Google scholar articles
Patricia Ann Shaw Department of Laboratory Medicine and Pathology, University Health Network, Toronto, Ontario, Canada PubMed articles Google scholar articles
Tracy Stockley Advanced Molecular Diagnostics Laboratory, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Igor Jurisica Krembil Research Institute, University Health Network, Toronto, Ontario, CanadaDepartments of Medical Biophysics and Computer Science, University of Toronto, Toronto, Ontario, CanadaInstitute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia PubMed articles Google scholar articles
Amit M Oza Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Stephanie Lheureux Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles

Citation

Mandilaras V, Garg S, Cabanero M, et al

TP53 mutations in high grade serous ovarian cancer and impact on clinical outcomes: a comparison of next generation sequencing and bioinformatics analyses

International Journal of Gynecologic Cancer Published Online First: 18 January 2019. doi: 10.1136/ijgc-2018-000087

Publication history

Received September 9, 2018
Revision received November 25, 2018
Accepted November 29, 2018
First published January 18, 2019.

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