You are here

Article Text

Article menu
Original Article
Serum lactate dehydrogenase levels in malignant germ cell tumors of ovary
  1. P.S. Patel*,
  2. V.M. Sharma*,
  3. G.N. Raval*,
  4. R.M. Rawal*,
  5. M.M. Patel*,
  6. D.B. Balar*,
  7. A. S. Kapadia† and
  8. D. D. Patel‡
  1. * Biochemistry Section, Division of Research, The Gujarat Cancer Society, †Department of Gynecological Oncology, ‡The Gujarat Cancer & Research Institute, Asarwa, Ahmedabad 380 016, India
  1. Address for correspondence: Dr P. S. Patel, In-charge, Biochemistry Section, Division of Research, The Gujarat Cancer Society, Asarwa, Ahmedabad 380 016, India.

Abstract

Serum lactate dehydrogenase (LDH) levels were examined in 24 patients with germ cell tumors of the ovary to evaluate the usefulness of the enzyme as a tumor maker. Lactate dehydrogenase levels were found to be significantly elevated (P<0.001) in these patients at the time of diagnosis as compared to the controls. Lactate dehydrogenase levels in patients with benign ovarian tumors and controls were comparable. The positive rate of LDH for malignant germ cell tumors of the ovary was 94.5%. The LDH values significantly declined in the patients who responded to treatment. Metastatic or recurrent disease resulted in increased LDH levels. The results indicate that LDH is a useful tumor marker for malignant germ cell tumors of the ovary.

  • germ cell tumors
  • lactate dehydrogenase
  • ovarian cancer
  • tumor markers

https://doi.org/10.1136/ijgc-00009577-199607000-00015

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.