The sensitivity of magnetic resonance (MR) imaging in predicting extracervical tumor invasion on the basis of the detection of a thinning of the uninvolved cervical stromal ring (3 mm or less) was compared to the sensitivity achieved by visualization of a complete stromal interruption. Fifty-seven consecutive patients with squamous carcinoma of the uterine cervix (FIGO stage IB-IIA), scheduled for radical surgery, were examined with axial and sagittal weighted MR sequences. The sensitivity in predicting extracervical involvement on the basis of the MR imaging visualization of a thinned stroma was 87.5%, whereas the sensitivity obtained by detection of a complete stromal interruption was 70%. Among women with a spared cervical stroma of more than 3 mm at MR imaging, only two had microscopic extracervical involvement at pathologic examination, accounting for a negative predictive value of 92.8%. The results of our study show a high concordance between MR imaging and pathologic findings, and indicate that the detection of an intact cervical stromal ring exceeding 3 mm at MR imaging is related to a very low risk of extracervical seeding of tumor. On the other hand, the detection of a thinned stromal ring is related to a high incidence of microscopic parametrial invasion. The information obtained by this imaging technique may therefore be extremely useful in accurate treatment planning for these patients.
- cervical cancer
- magnetic resonance imaging
- uterine neoplasms
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.