Introduction Mortality rates from advanced ovarian cancer are poor and regional variation exists. There have been important advances in treatment however, a significant proportion still die within the first 12 months. To improve survival overall, factors associated with short term mortality need to be identified.

Methods Patients with stage 3 and 4 high grade serous ovarian, fallopian tube and primary peritoneal carcinoma diagnosed in the West of Scotland between June 2021 and Dec 2022 were identified from the Multi-Disciplinary Team (MDT) database.

Results 119 patients identified. Median age 69 yr (42-94). Baseline characteristics and treatment (table 1). At data cut-off on 28-04-2024, 47 patients had died. The short-term mortality rates were 0-2m: 2.5%; 2-6m: 6.7%; 6-12m: 10%; >12m: 20.1%. 31.9% presented as an emergency. Median time from referral by GP to treatment: 2 months (range 0.5-4). 36.1% required inpatient treatment initially.

Conclusion/Implications The percentage of women dying within the 1^st year, presenting as an emergency and requiring initial inpatient treatment is high. Reducing the rate of emergency presentations and reducing timelines to treatment by raising awareness and improving diagnostic pathways is a priority. Investigation of factors associated with short term mortality is ongoing.