Article Text
Abstract
Introduction Early-stage cervical cancer is typically treated with Wertheim-Meigs’s conventional surgery, where lymph node metastasis is a critical prognostic factor. Sentinel lymph node mapping (SLN) offers a less invasive approach with reduced surgical morbidity.
Methods A retrospective cohort study analyzed data from 36 cervical cancer patients who underwent Wertheim-Meigs with SLN mapping using patent blue dye and intraoperative freezing at the Dr Arnaldo Vieira de Carvalho’s Cancer Insititute, Brazil, from February 2018 to March 2024, aproved by Ethical Comitee.
Results The average age was 47 years, with 61.11% White and 38.89% mixed-race patients. Preoperatively, 19.44% were diagnosed with adenocarcinoma, and 80.56% with squamous cell carcinoma (SCC). Post-surgery, 58.33% had SCC, 19.44% adenocarcinoma, and 22.22% were neoplasm-free. The mean tumor size was 2.9 cm (0.6 to 10.5 cm). Staging included 36.11% IA1, 38.89% IB1, 2.78% IB2, 2.78% IB3, 5.56% IIA1, 8.33% IIA2, 2.78% IIB, and 2.78% IIIB. A heterogeneous distribution chain of stained lymph nodes was observed: 41.67% in the external iliac, 2.78% in the common iliac, 13.89% in the internal iliac, 36.11% in the obturator, and 5.56% without stained lymph nodes.
Conclusion/Implications This study provides insights into the clinical and histological profile of cervical cancer patients undergoing sentinel lymph node mapping, demonstrating a heterogeneous distribution of stained lymph nodes with a detection rate of 94.44%, sensitivity of 100%, and specificity of 94.12%.