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EV080/#764  Abdominal vs. minimally invasive radical hysterectomy at hospital Clínico Universidad Católica de Chile: recurrence and mortality rates in early-stage cervical cancer
  1. Elisa Orlandini1,
  2. Magdalena Ruiz-Esquide2,
  3. Mauricio Cuello1 and
  4. Jorge Brañes1
  1. 1Pontificia Universidad Católica de Chile, Obstetrics Ang Gynecology. Gynecology Oncology, Santiago, Chile
  2. 2Pontificia Universidad Católica de Chile, Santiago, Chile

Abstract

Introduction Following the 2018 LACC trial, which reported lower survival rates with minimally invasive Radical hysterectomy (RH), questions have arisen about its suitability for early-stage cervical cancer. This study aims to compare disease-free and overall survival rates in patients undergoing open and minimally invasive RH at our institution.

Methods A retrospective review was conducted on early-stage cervical cancer patients (FIGO 2018 stages IA2, IB1, IB2, and IIA1) who underwent RH at Hospital Clínico Universidad Católica de Chile from 2008 to 2019. The main outcomes assessed were recurrence and mortality rates, hospital stay duration, and postoperative complications between the open and MIS groups.

Results 77 patients with early-stage cervical cancer underwent RH in our center between the mentioned dates, 42 had an open and 35 laparoscopic RH. The median follow-up time was 108 months. The 5-year OS was 94.8% in the open group, and 95.2% in the MIS group (p=0.9). There were 5 recurrences in the open RH and 6 in the MIS group (11.9 and 17.1%, p=0.8) (see tables 1). There were significant differences favoring MIS in mean hospital stay (6.5±0.3 vs. 4.4±0.3 days, p<0.0001) and in operating time for open (195 vs. 252 minutes, p<0.0001). However, there were no significant differences in intraoperative and postoperative complications or the need for adjuvant therapy.

Conclusion/Implications No significant differences were found in PFS and OS rates between open and minimally invasive RH. While MIS showed advantages in hospital stay and open surgery shorter operating time, both approaches had similar rates of complications and need for adjuvant therapy.

Abstract EV080/#764 Table 1

n° 1 PUC cohort demograhics

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