Introduction Adenocarcinoma accounts for 10–25% of all cervical cancers, most authors reported that it has a greater propensity to lymph node, ovarian and distant metastases. The analysis of prognostic factors in hysterectomy and lymphadenectomy specimens could add interesting to improve local and distant control for future patients. In this study we analyse prognosis factors for patients treated for adenocarcinoma of the uterine cervix.

Methods We conducted a retrospective study including patients followed and treated for adenocarcinoma of the cervix at Salah Azaiez Institute over the period from January 2004 to December 2020

Results Fifty patients were included in our study, the mean age was 58.19±13 years. The most frequent FIGO stage was stage II (38.6%). 5-year disease free survival (DFS) was 84% for the patients in stage I and 36% in stage II(p:0.004), it was 89% when tumour size < 3 cm while 64% when size > 3cm (p:0.002), patients with bulky disease had a 5-year DFS of 9%. patient age was a significant prognosis factor with a 5year DFS of 81% < 45 years 57% for patients > 45 years. 5-year DFS of 91% for negative lymph nodes versus 24%(p:0.001) for positive, 82% when stromal invasion <10 mm Vs 63% when <10mm (p:0.02)

Conclusion/Implications FIGO stage, nodal status, tumour size, depth of cervical invasion, surgical margin status, are correlated significantly with both DFS and OS, nodal status and is an independent prognostic factor.