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455 Cutaneous metastasis from a squamous cell carcinoma of the uterine cervix: report of three cases
  1. Nayssem Khessairi,
  2. Sakhri Saida,
  3. Ons Krimi,
  4. Hanen Bouaziz,
  5. Maher Slimene and
  6. Tarek Dhiab
  1. Surgical Oncology Department, Salah Azaiez Institute, Tunis, Tunisia

Abstract

Introduction/Background Cervical cancer is the second most common cancer in women worldwide after breast cancer. It has a generally good prognosis, often with merely loco-regional invasion. Extra pelvic hematogenous metastases are rare, and the most common sites are lung and liver. Skin metastases, though, are extremely rare, and their occurrence indicates a highly advanced stage of the disease.

Methodology We report, three cases of cutaneous metastases from squamous cell carcinoma treated in our institute between 2000 and 2023.

Results Three Caucasian female patients, aged respectively 42,45 and 61 years, were treated in our institute for squamous cell cervical cancer. Two patients presented a stade IIB tumors according to FIGO staging system. They were both treated with concomitant chemo-radiation followed by colpohysterectomy with pelvic lymphadenectomy. These two patients developed metachronous skin metastases after two and three years of disease free evolution respectively, affecting the thigh and the abdominal wall. The third patient presented a stage IVB cervical tumor with synchronous skin metastases affecting the left latero-thoracic wall and the scalp. Palliative chemotherapy was indicated for the three patients.

Conclusion Cutaneous metastases of cervical squamous cell carcinoma are extremely rare. Their prognosis is poor. Their treatment is palliative and poorly codified, based on chemotherapy. Regular and rigorous clinical and radiological monitoring of patients treated for cervical cancer is necessary to detect these metastases.

Disclosures No disclosures to declare.

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