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225 Thermal profiling of cervical carcinoma patients undergoing brachytherapy: a novel diagnostic approach
  1. Tatiana Rabin1,
  2. Noam Moyal2,
  3. Yair Zimmer3,
  4. Tal Kohen1,
  5. Shoshana Rosenberg1,
  6. Alexandra Rozenfeld1,
  7. Rafael Y Brzezinski1,
  8. Ofer Hadar2 and
  9. Oshrit Hoffer4
  1. 1Tel Aviv Medical Center, Tel-Aviv, Israel
  2. 2School of Electrical Engineering, Ben Gurion University, Bear-Sheva, Israel
  3. 3School of Medical Engineering, Afeka College of Engineering, Tel-Aviv, Israel
  4. 4School of Electrical Engineering, Afeka College of Engineering, Tel-Aviv, Israel


Introduction/Background Cervical cancer poses a significant global health threat, necessitating comprehensive treatment approaches. Brachytherapy stands out as a crucial component in combating this disease. The success of cervical cancer treatment relies heavily on the effective monitoring of tissue response, ensuring both the efficacy of treatment and the well-being of patients.

Methodology This study focused on nine patients who underwent thermal imaging assessments before and after a brachytherapy session involving a 5.5Gy treatment. To facilitate precise analysis, a novel algorithm was employed to automatically isolate the cervix in thermal images. This allowed for the calculation of key temperature parameters, including minimum, maximum, and average temperatures within the region of interest.

Results Malignant tumors exhibit distinct metabolic and perfusion rates, leading to temperature variations compared to healthy tissues. Temperature differences were quantified using a parameter defined as the difference between maximum and minimum temperatures divided by the average temperature. The analysis revealed a statistically significant difference in parameter values before radiation compared to those obtained after radiation (p = 0.01). These findings underscore the potential of thermal imaging in detecting tissue-specific changes in the cervix in response to local brachytherapy.

Conclusion In summary, the findings of this study highlight the promise of thermal imaging as a valuable tool for monitoring cervical brachytherapy. The ability to detect tissue-specific changes emphasizes the potential of thermal imaging in enhancing patient care and improving treatment outcomes in the battle against cervical carcinoma.

Disclosures The authors declare no conflicts of interest.

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