Introduction/Background Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is recognised as an effective treatment for peritoneal carcinomatosis, one of the causes of which is ovarian carcinomatosis. HIPEC is generally administered using an open or closed abdominal technique. Both techniques have their strengths and weaknesses, in term of safety and efficacity

Methodology to present an innovative technique that improves staff safety and efficiently pf the procedure while respecting the classic HIPEC standards

Results Remenber in the open abdominal technique, or ‘coliseum technique’, the abdominal contents are directly agitated manually, main known risk of exposure to chemotherapy agents. The closed technique, The abdominal contents are agitated from the outside through the abdominal wall, main known risk of non-homogeneity in the exposure of chemotherapy products, thermal injuries.. The technique we are proposing combines the two currently known procedures, hence the name half-open and half-closed. Before the cytoreduction surgery, a transparent film as part the operating field kit is placed, which adheres completely to the skin wall; after the surgery, we create a false skin using a latex field with an opening centred on the incision perimeter, which will be stapled to the skin and the fil (for safety reason, in order to limit the flow of liquid during manual agitation). The edges of the latex drape will be maintained and sealed by a retractable glass frame on coliseum’s dimensions with a 10 cm diameter hole in the center covered by a gel point (a safety feature to limit inhalation, and an efficiency feature to improve the heat circuit and exposure to the chemotherapy agents).

Conclusion the semi-open, semi-closed technique is a probably safe alternative as a guarantee of effectiveness and safety, but large studies deserve to be carried out in order to validate it as a standard technique.

Disclosures No disclosures.